|Active Ingredients||Role in cosmetic care|
Downregulating inflammatory cytokines like TNF-alpha, IL-1 Beta, and MMPs (Matrix metalloproteinase), while upregulating inflammatory cytokines like IL-4, IL-10 and TIMPs. Thus, MSC derived exosomes can reduce inflammation due to skin ageing.
The proteins like peroxiredoxins could reduce the oxidation state of cells under tremendous oxidative stress due to ageing. Thus, reducing oxidative stress on cells could improve their functions and survival.
These components are actively involved in maintaining cellular viabilities and preventing early cell death. The anti-apoptotic messengers these components are carrying along with the same is responsible for slow, stopping and/or reversing progression of ageing.
These components including exosomes are associated with optimization of damaged skin tissues with improved collagen type I/III ratios and normal organization of collagen fibres.
They are involved in regulation of immune cells like macrophages and T cells in different prototypes and are involved in activation of anti-inflammatory cytokines, preventing ageing.
By stimulating endothelial cell function, these cells are involved in vascularization leading to tissue regeneration
The pro-synthetic effects are helpful in activation of skin cells and enhance extracellular matrix production. Specific exosomes molecules are helpful in synthesis of collagen.
Proteins that are present in these active ingredients are important for induction of inactive DNA transcription.
Presently, cosmetic companies are using active ingredients from plants for the desired effects on skin care; however, it is very important to understand that skin care in our body is naturally controlled with the help of stem cells present within us. Due to ageing, these resident stem cells start losing their capacity to differentiate and regulate skin cells. Geriatric researchers have discovered that multiple factors are responsible for ageing, one of them is inflammatory role played by external stressors like pollution, diseased condition, diet etc.
We have identified the most potent sources of stem cells, isolated from Fetal tissues with in their naïve state. The active ingredients that we isolate from stem cells through unique technology are basically packed controlling codes, secreted by stem cells. Similar codes are inserted in other cells by hijacking them for the production of multiple proteins like collagen, secretion of anti-inflammatory markers for anti-ageing etc. Thus, these active ingredients open the miraculous way towards anti-ageing and longevity.These ingredients are being produced on a mass scale, quality assessed at each step of their development and before the release of the final batch.